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Title:
酵素架橋凝集体、及びこれを備えるマイクロリアクター
Document Type and Number:
Japanese Patent JP6454469
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a cross-linked enzyme aggregate which improves the durability without lowering the catalyst activity, thereby solving the problem about catalysts which lower or lose their catalyst activities by being subjected to reductive reaction.SOLUTION: The cross-linked enzyme aggregation of the invention has a structure where an enzyme molecule is cross-linked with a compound having imide ester groups as cross-linking functional groups. As the compound having imide ester groups as the cross-linking functional groups, a compound having two or more of imide ester groups in one molecule is preferable. It is preferable that the compound has the imide ester group at a terminal of a linear or branched hydrocarbon group having two or more carbons, or a terminal of two or more of the hydrocarbon groups bonded via one or more linkage groups.

Inventors:
Masaya Miyazaki
Mari Ikeda
Application Number:
JP2014008798A
Publication Date:
January 16, 2019
Filing Date:
January 21, 2014
Export Citation:
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Assignee:
Daicel Corporation
International Classes:
C12N9/96; B01J19/00; B81B1/00; C12M1/40; C12N9/04; C12N11/14
Domestic Patent References:
JP2012516926A
JP2010041973A
JP61111685A
JP62215387A
JP7097454A
JP56036048A
JP2008043245A
JP2000262281A
JP52034979A
JP9065877A
JP55148089A
JP2006238760A
JP2051064A
Foreign References:
WO2013071284A1
Other References:
J. Biol. Chem.,1972年,Vol.248, No.10,p.3470-3475
Biochem.,1975年,Vol.14, No.23,p.5233-5238
Attorney, Agent or Firm:
Yukihisa Goto
Yuki Hamei