Title:
ｔｒａｎｓ−８−クロロ−５−メチル−１−［４−（ピリジン−２−イルオキシ）−シクロヘキシル］−５，６−ジヒドロ−４Ｈ−２，３，５，１０ｂ−テトラアザ−ベンゾ［ｅ］アズレン及びその結晶形態の合成
Document Type and Number:
Japanese Patent JP6454707
Kind Code:
B2
Abstract:
The invention provides processes to manufacture substituted 1-[4-(Pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulenes. Also disclosed are compounds useful as intermediates in the methods of the invention.
Inventors:
Rotten Heusler, Benno
Trussardi, Rene
Hoffman-Emery, Fabine
Schwitter, Urs
Adan, Jean-Michel
Glassman, Olaf
Hartunk, Thomas
Orchid, frederik
Ralph Diodorne
Freger, Christoph
Bartels, Bjorn
Trussardi, Rene
Hoffman-Emery, Fabine
Schwitter, Urs
Adan, Jean-Michel
Glassman, Olaf
Hartunk, Thomas
Orchid, frederik
Ralph Diodorne
Freger, Christoph
Bartels, Bjorn
Application Number:
JP2016536746A
Publication Date:
January 16, 2019
Filing Date:
December 01, 2014
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D487/04; C07D243/14
Domestic Patent References:
| JP2012510441A | ||||
| JP2006517921A | ||||
| JP2007517857A |
Other References:
Journal of Organic Chemistry,2000年,65(3),p.655-666
Attorney, Agent or Firm:
Patent business corporation Tsukuni