Title:
核酸搬送制御デバイス及びその製造方法、並びに核酸シーケンシング装置
Document Type and Number:
Japanese Patent JP6472208
Kind Code:
B2
Abstract:
The present invention provides: a nucleic acid delivery controlling system in which a novel delay principle is utilized to greatly delay the nanopore passing rate of a nucleic acid strand, thereby enabling the stable analysis of a nucleotide sequence; a method for manufacturing the nucleic acid delivery controlling system; and a nucleic acid sequencing device. The present invention relates to a nucleic acid delivery controlling system, equipped with a passage through which a nucleic acid strand can pass, said nucleic acid delivery controlling system being characterized in that the passage through which a nucleic acid strand can pass has at least one nanochannel having multiple passages per one nanopore through which only one molecule of the nucleic acid strand can pass, the nanochannel has a microphase-separated structure composed of a block copolymer that is composed of a hydrophobic polymer chain and a hydrophilic polymer chain, and the nanochannel contains the hydrophilic polymer chain of the block copolymer as the main component.
Inventors:
Hiroshi Yoshida
Rena Akahori
Takanobu Haga
Rena Akahori
Takanobu Haga
Application Number:
JP2014217124A
Publication Date:
February 20, 2019
Filing Date:
October 24, 2014
Export Citation:
Assignee:
Hitachi High-Technologies Corporation
International Classes:
C12M1/00; B82Y5/00; B82Y40/00; C08F293/00; C12Q1/6869; G01N27/26
Domestic Patent References:
| JP2014074599A |
Foreign References:
| WO2012043028A1 |
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Satoshi Fujita