Title:
ＭＲにおける代謝マーカーとしての過分極エステル
Document Type and Number:
Japanese Patent JP6507101
Kind Code:
B2
Abstract:
The invention relates to a method of Magnetic Resonance (MR) detection, in particular 13C-MR detection, by using a diagnostic medium comprising a hyperpolarized ester, in particular ethyl acetoacetate. The method comprises the detection of the MR signal of a hyperpolarized 13C carboxylic ester and of its respective hyperpolarized metabolite.
Inventors:
Peaniru Rose Jenssen
Matilde Ho Leake
Magnus Carlson
Claudia Cabella
Sonia Colombo Sella
Luigi Miragori
Luca Venturi
Fabio Tedoldi
Matilde Ho Leake
Magnus Carlson
Claudia Cabella
Sonia Colombo Sella
Luigi Miragori
Luca Venturi
Fabio Tedoldi
Application Number:
JP2015555695A
Publication Date:
April 24, 2019
Filing Date:
January 30, 2014
Export Citation:
Assignee:
BRACCO IMAGING S.P.A.
International Classes:
A61B5/055
Domestic Patent References:
| JP2008508267A | ||||
| JP2014520606A | ||||
| JP2011506015A |
Foreign References:
| WO2011124672A1 |
Other References:
KENNEDY, B. W. C,Detection of hyperpolarized 13C labeled ketone bodies in vivo,PROCEEDINGS OF THE INTERNATIONAL SOCIETY FOR MAGNETIC RESONANCE IN MEDICINE,2012年 5月,V20,P4326
PERNILLE ROSE JENSEN,Hyperpolarized 1,3-13C2-Ethyl acetoacetate is a novel diagnostic metabolic marker of liver cancer,4TH INTERNATIONAL DNP SYMPOSIUM,2013年 8月28日,P101
PERNILLE ROSE JENSEN,Hyperpolarized 1,3-13C2-Ethyl acetoacetate is a novel diagnostic metabolic marker of liver cancer,4TH INTERNATIONAL DNP SYMPOSIUM,2013年 8月28日,P101
Attorney, Agent or Firm:
Takuji Yamada
Aoyama Aoi
Michiko Matsutani
Yasushi Ochiai
Aoyama Aoi
Michiko Matsutani
Yasushi Ochiai