Title:
精神障害の処置において使用するためのテトラゾール誘導体
Document Type and Number:
Japanese Patent JP6518789
Kind Code:
B2
Abstract:
The present invention relates to compounds of formula (I), wherein R1' is CH3 R1' is methyl, ethyl, CF3, CH2OH, cyclopropyl or cyano, or R1, and R1 may form together a 1,1-dioxo-tetrahydro-thiophen-3-yl ring; R2 is hydrogen, methyl, ethyl, isopropyl, tertbutyl, cyclopropyl or CF3; R3 is C1, F, CF3, methyl, methoxy, isopropyl or cyclopropyl; R4 is hydrogen, methyl, F or C1; or to a pharmaceutically acceptable salt or acid addition salt, to a racemic mixture, or to its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof for use in the treatment of schizophrenia, bipolar disorder, obsessive-compulsive disorder or autism spectrum disorder.
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Inventors:
Henner, Marius
Wichmann, Jurgen
Wichmann, Jurgen
Application Number:
JP2017555265A
Publication Date:
May 22, 2019
Filing Date:
April 19, 2016
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
A61K31/41; C07D257/04; A61P25/18; C07D409/12
Domestic Patent References:
| JP2010540585A | ||||
| JP2006151954A | ||||
| JP2011528658A |
Foreign References:
| WO2008000645A1 | ||||
| WO2009043780A1 |
Attorney, Agent or Firm:
Patent business corporation Tsukuni