Title:
組換え改変ワクシニアウイルスアンカラ（ＭＶＡ）ＲＳウイルス（ＲＳＶ）ワクチン
Document Type and Number:
Japanese Patent JP6523955
Kind Code:
B2
Abstract:
Provided herein are recombinant modified vaccinia virus Ankara (MVA) strains as improved vaccines against infection with Respiratory Syncytial Virus (RSV virus) and to related products, methods and uses. Specifically, provided herein are genetically engineered recombinant MVA vectors comprising at least one nucleotide sequence encoding an antigenic determinant of an RSV membrane glycoprotein and at least one nucleotide sequence encoding an antigenic determinant of an RSV nucleocapsid protein. Also provided herein are products, methods and uses thereof, e.g., suitable to affect an immune response in a subject, or suitable to diagnose an RSV infection, as well as to determine whether a subject is at risk of recurrent RSV infection.
Inventors:
Cheminai Cedric
Steigerwald Robin
Chaplin Paul
Steigerwald Robin
Chaplin Paul
Application Number:
JP2015524681A
Publication Date:
June 05, 2019
Filing Date:
March 15, 2013
Export Citation:
Assignee:
Bavarian Nordic Actiselskab
International Classes:
C12N7/04; A61K31/7088; A61K35/76; A61K48/00; A61P31/12; C12N15/45; C12N15/863
Domestic Patent References:
| JP2010522540A |
Foreign References:
| WO2012085936A1 | ||||
| WO2012089833A1 | ||||
| WO2011017442A1 |
Other References:
J. Virol.,1993年,Vol. 67, No. 7,p. 4086-4092
J. Virol.,1993年,Vol. 67, No. 2,p. 1044-1049
J. Exp. Med.,1997年,Vol. 186, No. 3,p. 421-432
J. Virol.,1993年,Vol. 67, No. 2,p. 1044-1049
J. Exp. Med.,1997年,Vol. 186, No. 3,p. 421-432
Attorney, Agent or Firm:
Mitsufumi Esaki
Blacksmith
Katsunori Uenishi
Ichiro Torayama
Blacksmith
Katsunori Uenishi
Ichiro Torayama