Title:
インフラマソーム活性化抑制剤
Document Type and Number:
Japanese Patent JP6533575
Kind Code:
B2
Abstract:
To provide a novel inflammasome inhibitor capable of inhibiting activation of inflammasome, the present inventors newly found that arctigenin reduces the amount of 1L-1² released and the amount of activated caspase-1 upon stimulation with ATP, palmitic acid, MSU and Poly(dA:dT) and thus has aneffect of inhibiting inflammasome activation. The present invention provides an inhibitor of inflammasome activation that comprises arctigenin as an active ingredient.
Inventors:
Shinpei Watanabe
Ayako Arai
Yuichi Takashiro
Satoshi Inamasu
Yomoda Satoshi
Akiko Ohno
Yuko Kitahara
Kanaya Taisaku
Ayako Arai
Yuichi Takashiro
Satoshi Inamasu
Yomoda Satoshi
Akiko Ohno
Yuko Kitahara
Kanaya Taisaku
Application Number:
JP2017525435A
Publication Date:
June 19, 2019
Filing Date:
February 08, 2017
Export Citation:
Assignee:
Kracie Holdings, Ltd.
International Classes:
A23L33/105
Foreign References:
| CN103127094A |
Other References:
New Food Industry 2014 vol.56 no.2 p.27-33
Attorney, Agent or Firm:
Rei Aihara