Title:
１７β‐ＨＳＤ１抑制剤のプロドラッグ
Document Type and Number:
Japanese Patent JP6545266
Kind Code:
B2
Abstract:
The present invention accordingly provides novel compounds of formula (I) wherein R1, R2, R3 and R4 are as defined in the claims. The invention further relates to their in treatment or prevention of steroid hormone dependent diseases or disorders, such as steroid hormone dependent diseases or disorders requiring the inhibition of the 17β-HSD1 enzyme and/or requiring the lowering of the endogenous estradiol concentration.
Inventors:
Hilbera, Lina
Koskimies, Pasi
La mintausta, list
Hakora, Maruyo
Ero lanta, email
Koskimies, Pasi
La mintausta, list
Hakora, Maruyo
Ero lanta, email
Application Number:
JP2017533562A
Publication Date:
July 17, 2019
Filing Date:
December 22, 2015
Export Citation:
Assignee:
Forend Pharma Limited
International Classes:
C07J43/00; A61K31/58; A61K31/662; A61P3/04; A61P13/02; A61P13/08; A61P13/10; A61P15/00; A61P17/00; A61P17/02; A61P17/18; A61P19/02; A61P27/12; A61P29/00; A61P35/00; A61P43/00
Domestic Patent References:
| JP2007510697A | ||||
| JP2006521338A |
Foreign References:
| US20060281710 |
Other References:
J. Med. Chem.,2006年,49,1325-1345
Attorney, Agent or Firm:
Hanabusa Patent and Trademark Office