Title:
多孔性粒子の製造方法
Document Type and Number:
Japanese Patent JP6557935
Kind Code:
B2
Abstract:
A method for producing porous particles includes (1) a step of preparing a solution of an amphiphilic substance by dissolving the amphiphilic substance in a mixed solvent capable of being freeze-dried, (2) a step of producing a precipitate containing the amphiphilic substance by cooling the solution obtained in step (1) to a temperature equal to or less than a phase separation temperature of the solution, and thereafter holding the solution at the temperature, and (3) a step of producing porous particles by freeze-drying the solution containing the precipitate obtained in the step (2).
Inventors:
Zhang Shaolin
Kawakami Wataru
Katsuhiko Ariga
Kawakami Wataru
Katsuhiko Ariga
Application Number:
JP2016560204A
Publication Date:
August 14, 2019
Filing Date:
November 16, 2015
Export Citation:
Assignee:
National Institute for Materials Science
International Classes:
A61K47/10; A61K9/14; A61K47/06; A61K47/08; A61K47/18; A61K47/22; A61K47/24
Domestic Patent References:
| JP6509547A | ||||
| JP58135804A | ||||
| JP3500650A |
Other References:
Qian,LEI 他,Controlled freezing and freeze drying: a versatile route for porous and micro-/nano-structured mater,J. Chem. Technol. Biotechnol.,2011年,Vol.86,pp.172-184
Teagarden,DIRK 他,Practical aspects of lyophilization using non-aqueous co-solvent systems,Eur. J. Pharm. Sci.,2002年,Vol.15,pp.115-133
原節子 他,大豆リン脂質クラスの新規分画法,成蹊大学理工学研究報告,2007年,Vol.44 No.2,pp.65-73
Teagarden,DIRK 他,Practical aspects of lyophilization using non-aqueous co-solvent systems,Eur. J. Pharm. Sci.,2002年,Vol.15,pp.115-133
原節子 他,大豆リン脂質クラスの新規分画法,成蹊大学理工学研究報告,2007年,Vol.44 No.2,pp.65-73
Attorney, Agent or Firm:
Yasushi Matsunuma
Norihiko Ara
Nishizawa Kazumi
Norihiko Ara
Nishizawa Kazumi