Title:
ＢＬＴ阻害活性を有する新規化合物およびこれを有効成分として含む炎症性疾患の予防または治療用組成物
Document Type and Number:
Japanese Patent JP6574517
Kind Code:
B2
Abstract:
The present invention relates to a novel compound showing leukotriene B4 receptor 2 (BLT2) inhibitory activity and a pharmaceutical composition, for preventing or treating inflammatory diseases, comprising same as an active ingredient. The inventors identified a novel compound containing BTL2 inhibitory activity, and experimentally confirmed that the present novel compound had an excellent effect on the enhancement of the cancer cell death, on the inhibition of the metastasis and chemotactic mobility, and on the anti-asthma activity. Therefore, the present novel compound can be used as a very effective pharmaceutical component for treating the inflammatory-related diseases.
Inventors:
Choi, Young Suk
Kim, Choi Hong
Lee, Kyung
Han, Hyo-Kyung
Wei, Chun Tong
Kwon, Jinson
Ku, Child
Kim, Choi Hong
Lee, Kyung
Han, Hyo-Kyung
Wei, Chun Tong
Kwon, Jinson
Ku, Child
Application Number:
JP2018503553A
Publication Date:
September 11, 2019
Filing Date:
July 23, 2016
Export Citation:
Assignee:
DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
International Classes:
C07C237/42; A61K31/167; A61K31/18; A61K31/192; A61K31/195; A61K31/197; A61K31/495; A61K31/5375; A61P1/06; A61P9/10; A61P11/06; A61P17/04; A61P19/02; A61P29/00; A61P35/00; A61P43/00; C07C233/18; C07C311/37; C07D295/192; C07D295/205
Domestic Patent References:
| JP2004513944A | ||||
| JP2005519994A | ||||
| JP2002532460A |
Foreign References:
| WO2006102760A1 | ||||
| WO2005102388A1 |
Attorney, Agent or Firm:
Patent Business Corporation Unias International Patent Office