Title:
ガレクチン−１（ＧＡＬ１）を中和するための抗ＧＡＬ１モノクローナル抗体およびその断片
Document Type and Number:
Japanese Patent JP6581982
Kind Code:
B2
Abstract:
The present invention is based, in part, on the discovery of galectin 1 (Gal1) epitopes against which anti-Gal1 agents can neutralize Gal1 function, as well as anti-Gal1 agents and methods useful for neutralizing Gal1 function.
Inventors:
Margaret A Ship
Jin Woo Yang
Scott Jay Rodig
Jin Woo Yang
Scott Jay Rodig
Application Number:
JP2016529855A
Publication Date:
September 25, 2019
Filing Date:
July 23, 2014
Export Citation:
Assignee:
Dana Faber Cancer Institute, Incorporated
International Classes:
C07K14/47; A61K31/7088; A61K35/76; A61K38/10; A61K39/39; A61K39/395; A61K48/00; A61P35/00; A61P37/02; C07K16/18; C07K16/46; C07K17/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/08; C12N15/12
Domestic Patent References:
| JP3502446A |
Foreign References:
| WO2011060272A1 |
Other References:
Blood,2011年,vol.117, no.16,p.4315-4322
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Kenji Tomita
Hiroshi Yamazaki
Kenji Tomita