Title:
ＩＬ−１２、ＩＬ−２３および／またはＩＦＮα応答のモジュレーターとして有用なアミド置換ヘテロ環式化合物
Document Type and Number:
Japanese Patent JP6585231
Kind Code:
B2
Abstract:
Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNa, by acting on Tyk-2 to cause signal transduction inhibition.
Inventors:
Ryan M. Muslin
David S. Weinstein
Stephen T. Robleski
John S. Tokalski
Amit Kumar
Douglas G Butt
Lynn Shuchun
Chunjiang Liu
Stephen H. Spagel
Jean Yang Lei
David S. Weinstein
Stephen T. Robleski
John S. Tokalski
Amit Kumar
Douglas G Butt
Lynn Shuchun
Chunjiang Liu
Stephen H. Spagel
Jean Yang Lei
Application Number:
JP2018094837A
Publication Date:
October 02, 2019
Filing Date:
May 16, 2018
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
A61K31/501; A61P1/00; A61P13/12; A61P17/06; A61P19/02; A61P29/00; A61P37/06; A61P43/00
Domestic Patent References:
| JP6407159B2 |
Attorney, Agent or Firm:
Norihito Yamao
Nagatoshi Shinagawa
Kure Hidenori
Kamahira Futami
Mizuhara Masahiro
Nagatoshi Shinagawa
Kure Hidenori
Kamahira Futami
Mizuhara Masahiro