Title:
新規免疫療法用分子およびその使用
Document Type and Number:
Japanese Patent JP6608282
Kind Code:
B2
Abstract:
The present invention relates generally to molecules such as peptides, polypeptides and proteins which interact immunologically with T lymphocytes in subjects having peanut allergy, or allergy to other tree nuts, and genetic sequences encoding same. These molecules are preferably immunointeractive with T cells in subjects having an allergy to the Ara h 1 allergen. The molecules of the present invention are useful in the development of diagnostic, therapeutic and prophylactic agents for conditions characterised by an aberrant, inappropriate or otherwise unwanted immune response to Ara h 1 or derivative or homologue thereof.
Inventors:
O'Hair Robin
Roland jennifer
Prickett Sara
Roland jennifer
Prickett Sara
Application Number:
JP2015538213A
Publication Date:
November 20, 2019
Filing Date:
October 30, 2013
Export Citation:
Assignee:
Alavax Pty Limited
International Classes:
A61K39/35; A61P37/06; A61P37/08; C12N15/29; C12Q1/04; G01N33/50
Foreign References:
| WO2011106645A1 |
Other References:
Jonathan H. DeLong, Bs,Ara h 1-Reactive T Cells in Peanut Allergic Individuals,J Allergy Clin Immunol. 2011 May ; 127(5): 1211~1218.e3
GenBank,24-MAY-1996, ACCESSION L34402,[retrieved on 2019.5.23], Retrieved from the Internet
西村泰治、蛋白質・核酸・酵素、2000年、45(7)、1205-1218頁
Prickett,S.,CD4+ T-cell epitope peptides with MHC-restriction diversity: Candidates for a peanut allergy therapeutic.,Allergy: European Journal of Allergy and Clinical Immunology, 2012 June, Vol. 67, Supp. SUPPL. 96, pp. 12. Abstract Number:25
GenBank,24-MAY-1996, ACCESSION L34402,[retrieved on 2019.5.23], Retrieved from the Internet
西村泰治、蛋白質・核酸・酵素、2000年、45(7)、1205-1218頁
Prickett,S.,CD4+ T-cell epitope peptides with MHC-restriction diversity: Candidates for a peanut allergy therapeutic.,Allergy: European Journal of Allergy and Clinical Immunology, 2012 June, Vol. 67, Supp. SUPPL. 96, pp. 12. Abstract Number:25
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office