Title:
ローヤルゼリー又はその加工物を有効成分とする血中ＣＣＬ１１濃度低減剤
Document Type and Number:
Japanese Patent JP6613422
Kind Code:
B1
Abstract:
【課題】本発明は、血中CCL11濃度を効果的にかつ簡便に低減させることができる、新たな手段を提供することを目的とする。【解決手段】本発明は、ローヤルゼリー又はその加工物を有効成分とする血中CCL11濃度低減剤、血中CCL11濃度低減用飲食品組成物及び血中CCL11濃度低減用医薬組成物に関する。本発明によれば、食経験があり、何ら深刻な副作用等が報告されていない安全な食材であるローヤルゼリーを経口的に摂取することで、血中CCL11濃度を効果的に低減することができる。【選択図】図１
Inventors:
Toyomaki Atsuto
Akane Miyazaki
Hayato Watanabe
Ichiro Kusumi
Koga farmer
Akane Miyazaki
Hayato Watanabe
Ichiro Kusumi
Koga farmer
Application Number:
JP2019032144A
Publication Date:
December 04, 2019
Filing Date:
February 25, 2019
Export Citation:
Assignee:
National University Corporation Hokkaido University
International Classes:
A23L33/10; A23L21/20; A61K35/644; A61P25/28; A61P37/08
Other References:
Villeda S. A., et al., "The ageing systemic milieu negatively regulates neurogenesis and cognitive function.",Nature. 2011 Aug 31, vol. 477, no. 7362, pp. 90-94.
Fernandez-Egea E., et al., "Cannabis use is associated with increased CCL11 plasma levels in young healthy volunteers.",Progress in neuro-psychopharmacology & biological psychiatry, 2013 Oct 1 (Epub 2013 Jun 29.), vol. 46, pp. 25-28.
Hattori N., et al., "Royal jelly facilitates restoration of the cognitive ability in trimethyltin-intoxicated mice.",Evidence-based complementary and alternative medicine, 2011 (Epub 2010 Oct 25), vol. 2011, Article ID 165968 (pp. 1-6)
Hattori N., et al., "Royal jelly and its unique fatty acid, 10-hydroxy-trans-2-decenoic acid, promote neurogenesis by neural stem/progenitor cells in vitro.",Biomedical research, 2007 Oct, vol. 28, no. 5, pp. 261-266.
Fernandez-Egea E., et al., "Cannabis use is associated with increased CCL11 plasma levels in young healthy volunteers.",Progress in neuro-psychopharmacology & biological psychiatry, 2013 Oct 1 (Epub 2013 Jun 29.), vol. 46, pp. 25-28.
Hattori N., et al., "Royal jelly facilitates restoration of the cognitive ability in trimethyltin-intoxicated mice.",Evidence-based complementary and alternative medicine, 2011 (Epub 2010 Oct 25), vol. 2011, Article ID 165968 (pp. 1-6)
Hattori N., et al., "Royal jelly and its unique fatty acid, 10-hydroxy-trans-2-decenoic acid, promote neurogenesis by neural stem/progenitor cells in vitro.",Biomedical research, 2007 Oct, vol. 28, no. 5, pp. 261-266.
Attorney, Agent or Firm:
Patent Assistance Corporation ip Assist Patent Office