Title:
免疫原性にされたストレスタンパク質ベースの治療用癌ワクチン
Document Type and Number:
Japanese Patent JP6616293
Kind Code:
B2
Abstract:
The invention describes a method for preparing a composition comprising tumour cell stress proteins, said method comprising the following steps: providing tumour cells in a culture medium; subjecting the tumour cells under i) to a stress with the result that these cells produce stress proteins in response to the stress; obtaining or recovering stressed tumour cells and/or stress proteins; treating the stressed tumour cells and/or the stress proteins obtained with a molecule or a process capable of rendering the stress proteins immunogenic, preferably a hapten or haptenization. The invention also describes a pharmaceutical composition comprising tumour cell stress proteins and/or tumour cells comprising stress proteins, these stress proteins being rendered immunogenic, and are in particular haptenized, and a pharmaceutically acceptable excipient.
Inventors:
Benoit pantur
Jill Deubier
Jill Deubier
Application Number:
JP2016524498A
Publication Date:
December 04, 2019
Filing Date:
October 15, 2014
Export Citation:
Assignee:
SEEFEL BIOTES
International Classes:
A61K39/00; A61K35/13; A61P35/00
Domestic Patent References:
| JP2008517946A | ||||
| JP2004507446A | ||||
| JP2003524583A |
Other References:
CAUDILL M M; LI Z,HSPPC-96: A PERSONALISED CANCER VACCINE,EXPERT OPINION ON BIOLOGICAL THERAPY,英国,INFORMA HEALTHCARE,2001年 5月,VOL:1, NR:3,PAGE(S):539 - 547,URL,http://dx.doi.org/10.1517/14712598.1.3.539
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Michiko Uehara
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Michiko Uehara