クランピングプローブ - Public University Corporation Osaka

Title:

クランピングプローブ

Document Type and Number:

Japanese Patent JP6629224

Kind Code:

B2

Abstract:

A method in which a mutant gene present in a gene pool mixedly with a large number of wild-type genes can be simply, inexpensively and sensitively detected is developed and provided. A clamping probe that is connected to a target nucleic acid molecule in two regions of first and second target nucleic acid complementary regions so that a wild-type target nucleic acid molecule and a mutant-type target nucleic acid molecule can be distinguished from each other depending on a difference in complementarity to these target nucleic acid molecules is provided.

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Inventors:

Ryo Tachibana
Toshizumi Tanabe

Application Number:

JP2016557835A

Publication Date:

January 15, 2020

Filing Date:

November 06, 2015

Export Citation:

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Assignee:

Public University Corporation Osaka

International Classes:

C12Q1/6876; C12Q1/6827; C12Q1/6886

Foreign References:

WO2011049343A1

Other References:

DAHSE R., et al.,PCR-based Testing for Therapy-related EGFR Mutations in Patients with Non-small Cell Lung Cancer,ANTICANCER RESEARCH,2008年,Vol.28,p.2265-2270,ISSN 0250-7005, 特に、第2265頁右欄第4行~第12行

Attorney, Agent or Firm:

Yusuke Hiraki
Satoshi Fujita
Seiichi Urushiyama

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