Title:
安定した可溶性ヘテロ二量体TCR
Document Type and Number:
Japanese Patent JP6640994
Kind Code:
B2
Abstract:
Disclosed are a heterodimeric TCR containing artificial interchain disulfide bond between the variable region of ± chain and the constant region of ² chain, a preparing method therefor and a use thereof.
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Inventors:
Lee
Application Number:
JP2018512466A
Publication Date:
February 05, 2020
Filing Date:
March 29, 2016
Export Citation:
Assignee:
GUANGDONG XIANGXUE LIFE SCIENCES, LTD.
International Classes:
C07K14/725; A61K38/17; A61P31/12; A61P35/00; A61P37/06; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12N15/63; C12P21/02
Domestic Patent References:
JP2013535199A | ||||
JP2005514006A | ||||
JP2006523437A |
Foreign References:
US20040048410 | ||||
WO2015022520A1 | ||||
WO2015011450A1 | ||||
WO2014206304A1 |
Attorney, Agent or Firm:
Nagoya International Patent Service Corporation