Title:
ユビキチン特異的プロテアーゼ７阻害薬としてのピロロ及びピラゾロピリミジン
Document Type and Number:
Japanese Patent JP6649388
Kind Code:
B2
Abstract:
The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula:where m, n, X1, X2, R1-R5, R5'and R6are described herein.
Inventors:
Ioanidis, Stefanos
Talbot, Adam Charles
Follows, Bruce
Back melter, alexander joseph
One, Minhwa
Campbell, Anne-Marie
Schmidt, Derby Rye
Garyn, David Joseph
Calavera, Justin A.
Dibold, Earl. Bruce
Ericsson, anna
Lancia, David Earl. Junior
Talbot, Adam Charles
Follows, Bruce
Back melter, alexander joseph
One, Minhwa
Campbell, Anne-Marie
Schmidt, Derby Rye
Garyn, David Joseph
Calavera, Justin A.
Dibold, Earl. Bruce
Ericsson, anna
Lancia, David Earl. Junior
Application Number:
JP2017535007A
Publication Date:
February 19, 2020
Filing Date:
December 29, 2015
Export Citation:
Assignee:
FORMA THERAPEUTICS,INC.
International Classes:
C07D487/04; A61K31/519; A61P1/04; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P13/12; A61P19/00; A61P19/02; A61P19/10; A61P25/00; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P31/12; A61P35/00; A61P35/04; A61P37/02; A61P43/00
Domestic Patent References:
| JP2014515345A | ||||
| JP2014527064A | ||||
| JP2004506737A |
Foreign References:
| WO2008116053A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto