Title:
骨関節炎処置を治療目的としたＣｏｌｌ２−１ペプチド及びそのニトロ化形態
Document Type and Number:
Japanese Patent JP6649399
Kind Code:
B2
Abstract:
The present invention provides a medicament comprising as active ingredient an inhibitor of Coll2-1 peptide activity and/or an inhibitor of Coll2-1NO2 peptide activity for use in the prevention and/or treatment of osteoarthritis. Further, the present invention provides a medicament comprising as active ingredient an inhibitor of Coll2-1 peptide activity and/or an inhibitor of Coll2-1NO2 peptide activity for use in the prevention and/or treatment of rheumatic and musculoskeletal diseases (RMDs).
More Like This:
Inventors:
Onrotan, Eve
Lambert, Cecil
Bordoli, Didier
Ronne, Francois
Lambert, Cecil
Bordoli, Didier
Ronne, Francois
Application Number:
JP2017550989A
Publication Date:
February 19, 2020
Filing Date:
December 07, 2015
Export Citation:
Assignee:
UNIVERSITE DE LIEGE
Universite Paris Descartes
Universite Paris Descartes
International Classes:
A61K39/395; A61P19/02; A61P29/00
Foreign References:
| WO2003076947A1 | ||||
| WO2009019657A1 |
Other References:
ZHU,Oral administration of type-ii collagen peptide 250-270 suppresses specific cellular and humoral immune response in collagen-induced arthritis,CLINICAL IMMUNOLOGY,米国,ACADEMIC PRESS,2006年10月11日,VOL:122, NR:1,PAGE(S):75 - 84,URL,http://dx.doi.org/10.1016/j.clim.2006.08.004
BARLAS BUYUKTIMKIN,Bifunctional peptide inhibitors suppress interleukin-6 proliferation and ameliorates murine collagen-induced arthritis,JOURNAL OF CLINICAL & CELLULAR IMMUNOLOGY,2014年,VOL:5, NR:6,PAGE(S):1-9,URL,http://dx.doi.org/10.4172/2155-9899.1000273
HENROTIN, Yves et al.,BMC Complementary and Alternative Medicine,2014年 5月17日,Vol. 14,Article No. 159,DOI: 10.1186/1472-6882-14-159
BARLAS BUYUKTIMKIN,Bifunctional peptide inhibitors suppress interleukin-6 proliferation and ameliorates murine collagen-induced arthritis,JOURNAL OF CLINICAL & CELLULAR IMMUNOLOGY,2014年,VOL:5, NR:6,PAGE(S):1-9,URL,http://dx.doi.org/10.4172/2155-9899.1000273
HENROTIN, Yves et al.,BMC Complementary and Alternative Medicine,2014年 5月17日,Vol. 14,Article No. 159,DOI: 10.1186/1472-6882-14-159
Attorney, Agent or Firm:
Michiharu Soga
Kajinami order
Kazuhiro Oyaku
Saori Sato
Kajinami order
Kazuhiro Oyaku
Saori Sato