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Title:
治療に使用するための、置換チエノピロロピリミジンリボヌクレオシド
Document Type and Number:
Japanese Patent JP6650074
Kind Code:
B2
Abstract:
A group of substituted thienopyrrolopyrimidine ribonucleosides of general formula I, in which R shows strong cytostatic and cytotoxic activities preferably against cancer cell lines of broad spectrum of diseases including tumors of various histogenetic origin.

Inventors:
Hosek, Michael
Michael Titi
Haiduha, Marian
Douzbac, Petr
Application Number:
JP2019517137A
Publication Date:
February 19, 2020
Filing Date:
June 29, 2016
Export Citation:
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Assignee:
Ustaf Organikke Hemier Abiohemie Academia Ved Zeer, Wei Wei
Univergita Parakeh Hove Oromot
International Classes:
C07H19/24; A61K31/7064; A61P35/00; A61P43/00
Domestic Patent References:
JP54090196A
JP2007504152A
Other References:
TICHY,M. et al.,Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides,Bioorganic & Medicinal Chemistry,2012年,Vol.20, No.20,p.6123-6133
TICHY,M. et al.,Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides,Bioorganic & Medicinal Chemistry,2013年,Vol.21, No.17,p.5362-5372
Attorney, Agent or Firm:
Harakenzo world patent & trademark