Title:
改変ＦＧＦ−２１ポリペプチドおよびその使用
Document Type and Number:
Japanese Patent JP6702962
Kind Code:
B2
Abstract:
Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encoded amino acid, and/or optionally fused to a fusion partner.
Inventors:
Paul E. Morin
Daniel Cohen
Lanjan mukersey
Timothy P. Riley
Rose sea christian
Dartha Lipovsek
Ray Camphausen
John Krupinski
Daniel Cohen
Lanjan mukersey
Timothy P. Riley
Rose sea christian
Dartha Lipovsek
Ray Camphausen
John Krupinski
Application Number:
JP2017522123A
Publication Date:
June 03, 2020
Filing Date:
October 23, 2015
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
A61K38/18; A61K47/60; A61P1/16
Domestic Patent References:
| JP2014500880A |
Foreign References:
| AU2012268895A1 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Kenji Tomita
Hiroshi Yamazaki
Kenji Tomita