Title:
スルファミドリンカー、スルファミドリンカーのコンジュゲート、及び調製の方法
Document Type and Number:
Japanese Patent JP6733993
Kind Code:
B2
Abstract:
The present invention relates to a compound comprising an alpha-end and an omega-end, the compound comprising on the alpha-end a reactive group Q1capable of reacting with a functional group F1present on a biomolecule and on the omega-end a target molecule, the compound further comprising a group according to formula (1) or a salt thereof:Said compound may also be referred to as a linker-conjugate. The invention also relates to a process for the preparation of a bioconjugate, the process comprising the step of reacting a reactive group Q1of a linker-conjugate according to the invention with a functional group F1of a biomolecule. The invention further relates to a bioconjugate obtainable by the process according to the invention.
Inventors:
Fercade, Jorg Marian Mathieu
Wadeeven, Maria Antonia
Fund Sand, Petras Josephus Jacobs Maria
Van berg, thunder sebastian
Van der ft, floris louis
Wadeeven, Maria Antonia
Fund Sand, Petras Josephus Jacobs Maria
Van berg, thunder sebastian
Van der ft, floris louis
Application Number:
JP2017517297A
Publication Date:
August 05, 2020
Filing Date:
October 05, 2015
Export Citation:
Assignee:
Shinafix B.V.
International Classes:
A61K47/64; A61K39/395; C07K16/00
Domestic Patent References:
JP49005988A | ||||
JP2001026574A | ||||
JP2007513110A | ||||
JP8027147A | ||||
JP2004501106A |
Foreign References:
WO2011037192A1 | ||||
WO2014144871A1 | ||||
WO2014065661A1 |
Other References:
Bioorganic & Medicinal Chemistry,2007年,Vol.15,p.7237-7247
Attorney, Agent or Firm:
Ikeda adult
Junichiro Sakamaki
Masakazu Noda
Junichiro Sakamaki
Masakazu Noda