Title:
抗酸化物質を含む皮膚充填剤組成物
Document Type and Number:
Japanese Patent JP6749993
Kind Code:
B2
Abstract:
The invention provides a method of making a dermal filler comprising the steps of providing hyaluronic acid; reacting a crosslinking agent with a Vitamin C derivative; adding the reacted crosslinking agent and Vitamin C derivative to the hyaluronic acid to form a crosslinked hyaluronic acid composition; and homogenizing and neutralizing the crosslinked hyaluronic acid composition to obtain an injectable gel.
Inventors:
Futian Liu
Nicholas Jay Manesis
Xiao Jie Yu
A Scene One Chee Chan
Nicholas Jay Manesis
Xiao Jie Yu
A Scene One Chee Chan
Application Number:
JP2018247976A
Publication Date:
September 02, 2020
Filing Date:
December 28, 2018
Export Citation:
Assignee:
ALLERGAN INDUSTRIE SAS
International Classes:
A61L27/20; A61L27/52; A61L27/54; A61L27/58
Domestic Patent References:
| JP2010535277A | ||||
| JP2011505362A | ||||
| JP2010511454A | ||||
| JP2009535453A |
Foreign References:
| WO2007018124A1 | ||||
| US20090017091 | ||||
| US20120283428 |
Other References:
Park D J et al,IN VITRO EVALUATION OF CONJUGATED HYALURONIC ACID WITH ASCORBIC ACID,Journal of Bone & Joint Surgery, British Volume,英国,2010年,Vol. 92-B No. SUPP I 115,URL,http://www.bjjprocs.boneandjoint.org.uk/content/92-B/SUPP_I/115.3
医学のあゆみ,2005年,Vol.214, No.2,p.145-148
医学のあゆみ,2005年,Vol.214, No.2,p.145-148
Attorney, Agent or Firm:
Michiko Matsutani
Yasushi Ochiai
Yasushi Ochiai