ＤＮＡ試料を分析するためのプローブ組及びその使用方法

Title:

ＤＮＡ試料を分析するためのプローブ組及びその使用方法

Document Type and Number:

Japanese Patent JP6785839

Kind Code:

B2

Abstract:

This disclosure provides, inter alia, a ligatable complex of formula X-A-B-Z, wherein in the complex sequences X, A, B and Z are ligatably adjacent to one another and held in position by a splint oligonucleotide, and wherein sequence A is a target fragment of a genome, sequence B identifies the locus from which the adjacent sequence A is derived. The ligatable complex can be used to identify a chromosome aneuploidy in cell free DNA, for example.

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Inventors:

Dar, Karl Oscar Fredrik
Ericson, Olof John
Carlson, Philip
Ruth, Fredrik

Application Number:

JP2018506431A

Publication Date:

November 18, 2020

Filing Date:

September 16, 2016

Export Citation:

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Assignee:

Vanadis Diagnostics

International Classes:

C12N15/11; C12Q1/6806; C12Q1/6837; C12Q1/6851; C12Q1/686; C12Q1/6876

Domestic Patent References:

JP2012522508A
JP2013544498A
JP2016537990A

Attorney, Agent or Firm:

Hiroshi Kobayashi
Norio Omori
Nao Fujita
Yasuhito Suzuki

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