Title:
胚様体の評価方法
Document Type and Number:
Japanese Patent JP6786077
Kind Code:
B2
Abstract:
The purpose of the present invention is to provide: a method for evaluating differential characteristic of an embryoid body obtainable from cultivation of pluripotent liver cells; a method for screening an embryoid body obtainable from cultivation of pluripotent liver cells; a method for modifying myocardiac cells from pluripotent liver cells; a cell population comprising an embryoid body obtained by the screening method and/or differentiation-induced cells obtained by differentiation-inducing the embryoid body; a pharmaceutical composition comprising the embryoid body and/or the cell population; and a method for producing the pharmaceutical composition. The purpose is achieved by a method for evaluating differential characteristic of an embryoid body obtainable from cultivation of pluripotent liver cells, the method comprising a step for measuring one or more morphological characteristics of the embryoid body.
Inventors:
Yoshiki Sawa
Shigeru Miyagawa
Taro Nagai
Kazumasa Yamaki
Kenji Oyama
Fumaya Ohashi
Shigeru Miyagawa
Taro Nagai
Kazumasa Yamaki
Kenji Oyama
Fumaya Ohashi
Application Number:
JP2020500980A
Publication Date:
November 18, 2020
Filing Date:
February 20, 2019
Export Citation:
Assignee:
National University Corporation Osaka University
Dai Nippon Printing Co.,Ltd.
Terumo Corporation
Dai Nippon Printing Co.,Ltd.
Terumo Corporation
International Classes:
C12Q1/02; C12N5/0735; C12N5/077
Other References:
Biomaterials,2009年 9月30日,Vol.30, No.26,pp.4384-4389
Proc. Natl. Acad. Sci.,2009年10月 6日,Vol.106, No.40,pp.16978-16983
Biomaterials,2010年 3月,Vol.31, No.7,pp.1885-1893
Proc. Natl. Acad. Sci.,2009年10月 6日,Vol.106, No.40,pp.16978-16983
Biomaterials,2010年 3月,Vol.31, No.7,pp.1885-1893
Attorney, Agent or Firm:
Kiyoji Kuzuwa
Kenichi Sugie
Kenichi Sugie