Title:
ＧＤＦ−１５を減少させるためのセレラキシンの使用
Document Type and Number:
Japanese Patent JP6820748
Kind Code:
B2
Abstract:
Growth differentiation factor 15 (GDF-15) is a stress-responsive cytokine known to be associated with adverse events in heart failure patients. The use of serelaxin has been shown to affect GDF-15 levels at baseline and decreases in GDF-15 levels over time. Measuring GDF-15 levels allows a healthcare provider to accurately predict pulmonary load in patients with pulmonary congestion.
Inventors:
Prescott, Margaret Forney
Jean, Emin
Darke, Marion
Thomas Severin
Jean, Emin
Darke, Marion
Thomas Severin
Application Number:
JP2016572697A
Publication Date:
January 27, 2021
Filing Date:
June 10, 2015
Export Citation:
Assignee:
Novartis Age
International Classes:
A61K38/16; A61P11/00; G01N33/68
Domestic Patent References:
| JP2011520918A | ||||
| JP2010528275A | ||||
| JP2013040174A | ||||
| JP2009545735A |
Other References:
Curr Heart Fail Rep., 2012, Vol.9, p.337-345
Lancet, 2013,Vol.381, p.29-39
Eur Heart J., 2013, Vol.34, p.3128-3136
Lancet, 2013,Vol.381, p.29-39
Eur Heart J., 2013, Vol.34, p.3128-3136
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Tomohiro Maruyama
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Tomohiro Maruyama
Yasuhito Suzuki