Title:
ブロモドメインＢＲＤ９の阻害剤としての新規ピリジノンおよびイソキノリノン
Document Type and Number:
Japanese Patent JP6857606
Kind Code:
B2
Abstract:
The present invention encompasses compounds of general formula (I) wherein the groups R1 to R9, X1 and X2 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, e.g. cancer, pharmaceutical preparations containing such compounds and their uses as a medicament.
Inventors:
Martin Leticia
Stular Stefen
Cockkf Loft Xiao-Lin
Stular Stefen
Cockkf Loft Xiao-Lin
Application Number:
JP2017546629A
Publication Date:
April 14, 2021
Filing Date:
March 04, 2016
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07D213/64; A61K31/4375; A61K31/4412; A61K31/4427; A61K31/444; A61K31/472; A61K31/4725; A61K31/496; A61K31/519; A61P35/00; C07D217/24; C07D401/10; C07D401/12; C07D401/14; C07D471/04
Domestic Patent References:
| JP2017533249A | ||||
| JP2000504303A | ||||
| JP2007510689A | ||||
| JP7500321A | ||||
| JP2016533397A |
Foreign References:
| WO2013142390A1 |
Other References:
REGISTRY(STN)[online],[検索日 2019.11.20]CAS登録番号1484253-92-0、1482890-58-3、1476107-82-0、1467229-54-4、1465607-29-7
Attorney, Agent or Firm:
Shinichiro Tanaka
Disciple Maru Ken
▲吉▼田 和彦
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Akizawa
Disciple Maru Ken
▲吉▼田 和彦
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Akizawa