Title:
皮膚の健康の評価方法
Document Type and Number:
Japanese Patent JP6867805
Kind Code:
B2
Abstract:
Provided is a method for evaluating skin health, which method comprises: preparing a lipid sample from collected stratum corneum of skin of a subject; determining the quantities of a ceramide component A and a ceramide component B contained in the prepared lipid sample of the subject, the ceramide component A being selected from the group consisting of a non-hydroxyacyl-phytosphingosine ceramide component, a non-hydroxyacyl-6-hydroxysphingosine ceramide component, an ester-ω-hydroxyacyl-6-hydroxysphingosine ceramide component, and an ester-ω-hydroxyacyl-phytosphingosine ceramide component, and the ceramide component B being selected from the group consisting of a non-hydroxyacyl-sphingosine ceramide component and an α-hydroxyacyl-sphingosine ceramide component; calculating the ratio of the determined quantity of the ceramide component A to the determined quantity of the ceramide component B; and evaluating skin health of the subject from the calculated ratio.
Inventors:
Jun Ishikawa
Yokose Urara
Kyoko Shima
Yuki Morokuma
Yokose Urara
Kyoko Shima
Yuki Morokuma
Application Number:
JP2016254280A
Publication Date:
May 12, 2021
Filing Date:
December 27, 2016
Export Citation:
Assignee:
Kao Corporation
International Classes:
G01N33/50; G01N27/62; G01N30/72; G01N30/88; G01N33/92
Domestic Patent References:
| JP2008261741A |
Other References:
横瀬うららほか,角層セラミドによる肌性状の新規指標,日本香粧品学会誌,2015年 9月30日,Vol. 39, No. 3,p. 196
手塚正ほか,種々の皮膚疾患の経表皮水分蒸散量(TEWL)の変化,皮膚,1990年 4月,Vol. 31, No. 2,p. 153-156
芋川玄爾,皮膚角質細胞間脂質の構造と機能,油化学,1995年,Vol. 44, No. 10,p. 751-766
ISHIKAWA, J. et al.,Changes in the Ceramide Profile of Atopic Dermatitis Patients,Journal of Investigative Dermatology,2010年 6月24日,Vol. 130,p. 2511-2514
ANGELBECK-SCHULZE, M. et al.,Canine epidermal lipid sampling by skin scrub revealed variations between different body sites and n,BMC Veterinary Research,2014年 6月12日,Vol. 10, No. 152,p. 1-10
手塚正ほか,種々の皮膚疾患の経表皮水分蒸散量(TEWL)の変化,皮膚,1990年 4月,Vol. 31, No. 2,p. 153-156
芋川玄爾,皮膚角質細胞間脂質の構造と機能,油化学,1995年,Vol. 44, No. 10,p. 751-766
ISHIKAWA, J. et al.,Changes in the Ceramide Profile of Atopic Dermatitis Patients,Journal of Investigative Dermatology,2010年 6月24日,Vol. 130,p. 2511-2514
ANGELBECK-SCHULZE, M. et al.,Canine epidermal lipid sampling by skin scrub revealed variations between different body sites and n,BMC Veterinary Research,2014年 6月12日,Vol. 10, No. 152,p. 1-10
Attorney, Agent or Firm:
Patent corporation Iida and Partners
Toshizo Iida
Hirokazu Hoshino
Toshizo Iida
Hirokazu Hoshino