Title:
外用剤及び外用剤の製造方法
Document Type and Number:
Japanese Patent JP6869500
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide an external preparation having an excellent moisture transpiration suppression effect and to provide a method for producing an external preparation.SOLUTION: There is provided an external preparation which comprises a hydrating oil agent, water and a closed endoplasmic reticulum formed by an amphiphilic substance or polycondensation polymer particles having a hydroxyl group, wherein the concentration of the hydrating oil agent is more than 0.015 mass% and a part of the hydrating oil agent is dispersed in an oil gel in a lyotropic spherical liquid crystal state. There is provided a method for producing an external preparation, which comprises a step of dispersing an O/W type emulsified liquid obtained by emulsifying and dispersing a hydrating oil agent in a water phase with an emulsifier composed of a closed endoplasmic reticulum formed by an amphiphilic substance in a water phase or polycondensation polymer particles having a hydroxyl group in an oil gel as a continuous phase, wherein at least a part of the hydrating oil agent forms a lyotropic spherical liquid crystal and the blending amount of the hydrating oil agent is 0.015 mass% or more relative to the external preparation.SELECTED DRAWING: Figure 1
More Like This:
Inventors:
Kazuo Tajima
Yoko Imai
Kana Miyasaka
Mizuguchi Yamaguchi
Kenji Yoshida
Kinya Takagaki
Yoko Imai
Kana Miyasaka
Mizuguchi Yamaguchi
Kenji Yoshida
Kinya Takagaki
Application Number:
JP2016250048A
Publication Date:
May 12, 2021
Filing Date:
December 22, 2016
Export Citation:
Assignee:
Kanagawa University
Toyo Shinyaku Co., Ltd.
Toyo Shinyaku Co., Ltd.
International Classes:
A61K8/06; A61K8/34; A61K8/73; A61Q5/00; A61Q19/00
Domestic Patent References:
| JP2014101294A |
Attorney, Agent or Firm:
Masayuki Masabayashi
Hayashi Ichiyoshi
Hayashi Ichiyoshi