新規な選択的１１−ベータ−ヒドロキシステロイド脱水素酵素１型

Japanese Patent JP6874250

B2

The present invention relates to novel selective 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors and the use thereof to prevent age-induced skin structure and function defects.

WO/2012/054090	METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUNDS
JP2001192319	TRANSPARENT OR TRANSLUCENT EMULSION, METHOD FOR PRODUCING THE SAME AND COSMETIC USING THE SAME
JPH05124948	MEDICINE FOR EXTERNAL USE CAPABLE OF INHIBITING MELANOGENESIS

Boudon, Stephanie
Geotti-Bianquini, Clowns
Hail, mark
Jackson, Irene
Shrifuku-Pocharco, Alexander

JP2017567119A

May 19, 2021

July 07, 2016

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DSM IP ASSETS B.V.

A61K8/49; A61K31/445; A61K31/5375; A61K31/55; A61Q19/08; C07D211/16; C07D265/30; C07D295/192; C07D401/10

KR1020140071892A

Yanzhao Wang, 外5名,A general ligand design for gold catalysis allowing ligand-directed anti-nucleophilic attack of alkynes,NATURE COMMUNICATIONS,2014年 4月 7日,VoL.5,p.4470/1-4470/8
Bengu Sezen, 外1名,Selective and Catalytic Arylation of N-Phenylpyrrolidine:sp3 C-H Bond Functionalization in the Absence of a Directing Group,JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2005年 4月20日,VoL.127,No.15,p.5284-5285
Sylvia Lauwagie, 他1名,Expenditious Synthesis of 2-Aryl Substituted Imidazolines and Imidazoles,HETEROCYCLES,2006年 4月11日,Vol.68, No.6,p.1149-1162

Ikeda adult
Yoshinori Shimizu
Junichiro Sakamaki

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