Title:
細胞表面上にペプチドを提示するためのシステム
Document Type and Number:
Japanese Patent JP6876628
Kind Code:
B2
Abstract:
The subject-matter of the present application concerns fusion proteins based on tetraspanin proteins, in which the extracellular loop is replaced in whole or in part by peptide sequences of a different composition and also their production and use as transport vehicle. The disclosed fusion proteins are anchored in the membrane of cells and can be used to present foreign peptides fused with them on the cell surface.
Inventors:
Ivanusic, Daniel
Application Number:
JP2017564948A
Publication Date:
May 26, 2021
Filing Date:
March 04, 2016
Export Citation:
Assignee:
Peter und Traud Engelhorn-Stiftung Tour Fairderung der Lebens Wissenschachten
International Classes:
C12N15/09; A61K35/12; A61K39/00; A61K47/65; A61P37/04; C07K14/705; C07K17/02; C07K19/00; C12N5/10; C12N15/62
Domestic Patent References:
| JP2015500826A |
Foreign References:
| WO2014186649A1 |
Other References:
Ryu F et al,Cell Structure and Function,2000年,25,317-327
Stickney Z et al,Biochem Biophys Res Commun,2016年 2月18日,472,53-59
Stickney Z et al,Biochem Biophys Res Commun,2016年 2月18日,472,53-59
Attorney, Agent or Firm:
Seiji Ohno
Yuko Matsuniya
Umeda Shinsuke
Hiroshi Morita
Tomoe Konno
Nobuto Oki
Yuko Matsuniya
Umeda Shinsuke
Hiroshi Morita
Tomoe Konno
Nobuto Oki