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Title:
新規抗PD−1抗体
Document Type and Number:
Japanese Patent JP6883579
Kind Code:
B2
Abstract:
The present disclosure provides monoclonal antibodies against protein programmed cell death 1 (PD-1), which can block the binding of PD-1 ligands to PD-1, and therefore block the inhibitory function of PD-1 ligands on PD-1 expressing T cells. The antibodies of disclosure provide very potent agents for the treatment of multiple cancers via modulating human immune function.

Inventors:
Tsuen, Yong
lysine
Chen, Chi Shen
Application Number:
JP2018526985A
Publication Date:
June 09, 2021
Filing Date:
August 11, 2016
Export Citation:
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Assignee:
Wuxi Biologics (Cayman) Incorporated
Open Monoclonal Technology, Incorporated
International Classes:
C12N15/13; A61K39/395; A61P31/12; A61P35/00; A61P37/04; A61P43/00; C07K16/28; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/06; C12N15/63
Domestic Patent References:
JP2010500872A
JP2006521783A
JP2009155338A
Foreign References:
WO2013059524A1
WO2012056407A1
US20150203579
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto