Title:
限外ろ過膜を用いたオリゴ糖ペプチドの精製法
Document Type and Number:
Japanese Patent JP6887957
Kind Code:
B2
Abstract:
The purpose of the present invention is to purify an SGP substance with high efficiency and in a simple manner. The present invention provides: a method for purifying an SGP substance by means of cross-flow ultrafiltration, said method being characterized by comprising a step of subjecting an aqueous solution containing the SGP substance to a cross-flow ultrafiltration treatment using a primary membrane through which the SGP substance can pass and protein-type impurities cannot pass to produce a filtrate (step A) and a step B of subjecting the filtrate produced in step A to a cross-flow ultrafiltration treatment using a secondary membrane through which the SGP substance cannot pass and low-molecular-weight impurities can pass to produce a concentrated solution (step B); and others.
Inventors:
Takashi Onuki
Takahiro Miyauchi
Takahiro Miyauchi
Application Number:
JP2017558249A
Publication Date:
June 16, 2021
Filing Date:
December 22, 2016
Export Citation:
Assignee:
Daiichi Sankyo Co., Ltd.
International Classes:
C07K1/34; C07K1/18; C07K1/20; C07K9/00
Domestic Patent References:
| JP6245784A | ||||
| JP8099988A | ||||
| JP2007137875A | ||||
| JP2003012693A | ||||
| JP2010274260A |
Foreign References:
| WO2014208742A1 |
Other References:
KOKETSU M., et al.,An efficient preparation and structural characterization of sialylglycopeptides from protease treated Egg Yalk,Journal of Carbohydrate Chemistry,1995年,Vol.14, No.6,p.833-841
萩原文二,橋本光一編,膜による分離法,株式会社講談社,1982年10月10日,p.187-188,特に第188頁図5.5
ポール・限外ろ過デバイス, 日本ポール株式会社, 2011, p.1-16
萩原文二,橋本光一編,膜による分離法,株式会社講談社,1982年10月10日,p.187-188,特に第188頁図5.5
ポール・限外ろ過デバイス, 日本ポール株式会社, 2011, p.1-16
Attorney, Agent or Firm:
Kimiki Ishibashi
Noriko Kitano
Toshiyasu Takemoto
Reiko Kanehara
Noriko Kitano
Toshiyasu Takemoto
Reiko Kanehara