Title:
p97のフラグメントおよびその使用
Document Type and Number:
Japanese Patent JP6889199
Kind Code:
B2
Abstract:
Provided are fragments of human p97 (melanotransferrin) polypeptides having blood-brain barrier (BBB) transport activity, including variants and combinations thereof, conjugates comprising the p97 fragments, and related methods of use thereof, for instance, to facilitate the delivery of therapeutic or diagnostic agents across the BBB and into the central nervous system.
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Inventors:
Timothy Vitalis
Line hard gabular
Line hard gabular
Application Number:
JP2019056849A
Publication Date:
June 18, 2021
Filing Date:
March 25, 2019
Export Citation:
Assignee:
Bio Assist Technologies, Inc.
International Classes:
C07K14/47; A61K39/395; A61K45/00; A61K47/64; A61P9/00; A61P21/00; A61P21/04; A61P25/00; A61P25/02; A61P25/14; A61P25/16; A61P25/28; A61P29/00; A61P31/04; A61P31/12; A61P33/00; A61P35/00; A61P35/02; A61P37/06; C07K7/08; C07K16/18; C07K16/24; C07K16/30; C07K16/40; C07K19/00
Domestic Patent References:
JP2005509144A |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto