Title:
ＴＮＦＲＳＦ１４／ＨＶＥＭタンパク質およびその使用の方法
Document Type and Number:
Japanese Patent JP6890546
Kind Code:
B2
Abstract:
In some aspects the present invention provides methods for the treatment of B-cell lymphomas. Some such methods involve administration of HVEM ectodomain polypeptides, anti-HVEM antibodies, or anti-BTLA antibodies to subjects in need thereof. Some such methods involve use of CAR T cells, such as CD19-specific CAR T cells. The present invention also provides compositions useful in such methods. These and other embodiments of the present invention and described further herein.
Inventors:
Michael Henry Boyce
Hans Guido Wendell
Darin Saloum
Hans Guido Wendell
Darin Saloum
Application Number:
JP2017551675A
Publication Date:
June 18, 2021
Filing Date:
April 04, 2016
Export Citation:
Assignee:
Memorial Sloan Kettering Cancer Center
International Classes:
C12N15/63; C12N5/10
Domestic Patent References:
| JP2002540083A |
Foreign References:
| WO2013074738A1 | ||||
| WO2014127261A1 | ||||
| WO2014134165A1 |
Attorney, Agent or Firm:
Samejima Mutsumi
Kenji Tomita
Fumio Inai
Manami Sasakura
Kenji Tomita
Fumio Inai
Manami Sasakura