Title:
結合エピトープを含有する融合タンパク質を封入する粒子
Document Type and Number:
Japanese Patent JP6904959
Kind Code:
B2
Abstract:
The present invention provides compositions comprising biodegradable particles that encapsulate two or more epitopes linked together by one or more linkers that are susceptible to cleavage by specific proteases. The present invention further provides methods for inducing antigen-specific tolerance and protective immune responses and for the treatment inflammatory diseases, such as autoimmune diseases, allergies, cancers, or infectious diseases.
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Inventors:
Getz, Daniel Earl.
Application Number:
JP2018534626A
Publication Date:
July 21, 2021
Filing Date:
January 04, 2017
Export Citation:
Assignee:
Cool Pharmaceuticals Development Company, Inc.
International Classes:
A61K9/51; A61K38/00; A61K39/00; A61K39/35; A61K39/395; A61K47/65; A61P35/00; A61P37/02; C07K19/00
Foreign References:
| WO2015023796A1 | ||||
| US20120010394 | ||||
| US20110070252 |
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito