Title:
ケモカイン受容体のモジュレーター
Document Type and Number:
Japanese Patent JP6923522
Kind Code:
B2
Abstract:
Compounds are provided as chemokine inhibitors having the structure:
Inventors:
Shi Chen
Dean Earl. Dragori
Junhwa Fan
Yaroslav Kalisiak
Antoni Krasinski
Manmohan Lady Releti
Benkat Mari
Jeffrey McMahon
Razinder Shin
Yuko Tanaka
Chu Yang
Chao Yui
Pengley Jane
Dean Earl. Dragori
Junhwa Fan
Yaroslav Kalisiak
Antoni Krasinski
Manmohan Lady Releti
Benkat Mari
Jeffrey McMahon
Razinder Shin
Yuko Tanaka
Chu Yang
Chao Yui
Pengley Jane
Application Number:
JP2018526119A
Publication Date:
August 18, 2021
Filing Date:
November 17, 2016
Export Citation:
Assignee:
Chemocentrix, Incorporated
International Classes:
C07D209/46; A61K31/4025; A61K31/4035; A61K31/41; A61K31/4155; A61K31/4178; A61K31/422; A61K31/4439; A61K31/454; A61K31/506; A61K45/00; A61P9/10; A61P11/00; A61P17/00; A61P17/06; A61P19/02; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/02; A61P37/06; A61P43/00; C07D401/12; C07D405/12; C07D405/14; C07D409/12; C07D413/12
Foreign References:
| WO2002083624A1 | ||||
| WO2004011418A1 | ||||
| WO2013061005A1 |
Other References:
Michael P.Dwyer et al,Discovery of 2-Hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5-methylfuran-2-yl)propyl]amino]-3,4-dioxo-cyclobut-1-enylamino}benzamide(SCH527123):A Potent, Orally Bioavailable CXCR2/CXCR1 Receptor Antagonist,J. Med. Chem.,2006年,49,7603-7606
Purakkattle Biju et al,"3,4-diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists",Bioorganic & Medicinal Chemistry Letters,2008年,18,228-231
Purakkattle Biju et al,"3,4-diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists",Bioorganic & Medicinal Chemistry Letters,2008年,18,228-231
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Sachiko Okabe
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Sachiko Okabe