Title:
コウジ酸ポリマー
Document Type and Number:
Japanese Patent JP6930918
Kind Code:
B2
Abstract:
A controlled release system for kojic acid having improved stability has been identified. To minimize degradation, kojic acid was incorporated into a hydrolytically degradable polymer (e.g., a polycarbonate-ester)). By synthesizing polymer precursors containing kojic acid-linker-kojic acid chemical structures, versatile monomers were developed that can be used to modulate polymer properties. Additionally the synthetic method lends itself to the development of other polymer systems. Polymers having one or more groups that will yield kojic acid upon degradation of the polymer backbone, as well as methods of use thereof are described.
Inventors:
Kathryn Urich
Kelvin Smith
Jonathan Fig
Kelvin Smith
Jonathan Fig
Application Number:
JP2017553081A
Publication Date:
September 01, 2021
Filing Date:
April 11, 2016
Export Citation:
Assignee:
Rutgers, The State University of New Jersey
International Classes:
C08G63/18; A61K8/84; A61K31/351; A61K47/59; A61P17/00; A61P43/00; A61Q1/02; A61Q19/00
Domestic Patent References:
| JP8245722A | ||||
| JP2008120884A |
Foreign References:
| CN102372845A | ||||
| WO2002053562A1 | ||||
| US2986553 |
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe