Title:
ｓｔｒｅｐタグ特異的キメラ受容体およびその使用
Document Type and Number:
Japanese Patent JP7407701
Kind Code:
B2
Abstract:
The present disclosure provides tag-specific fusion proteins for selectively detecting molecules containing a strep-tag peptide or cells containing a strep-tag peptide. Disclosed embodiments include tag-specific fusion proteins that can be used in reagents and methods for monitoring and/or modulating immunotherapy cells that express a strep-tag peptide. Embodiments including fusion proteins that specifically bind tagged targets and recombinant host cells comprising polynucleotides encoding the tag-specific fusion proteins are also provided. Immunotherapy cells that express a tagged marker are also provided.
Inventors:
Liu, Linfeng
Liddell, Stanley Earl.
Busch, Dirk
Frösl, Jimone
Liddell, Stanley Earl.
Busch, Dirk
Frösl, Jimone
Application Number:
JP2020513309A
Publication Date:
January 04, 2024
Filing Date:
September 06, 2018
Export Citation:
Assignee:
Fred Hutchinson Cancer Center
Technish Univergitate Munich
Technish Univergitate Munich
International Classes:
C07K19/00; A61K31/7088; A61K47/68; A61K48/00; A61P35/00; A61P37/04; C07K14/725; C07K16/12; C07K16/28; C12N5/10; C12N15/12; C12N15/13; C12N15/31; C12N15/62; C12N15/867
Domestic Patent References:
| JP2017501702A | ||||
| JP2017507919A | ||||
| JP2021500854A | ||||
| JP2020505034A |
Foreign References:
| WO2016176651A2 |
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto