Document Type and Number:
Japanese Patent JPH0244837
Kind Code:
B2
Abstract:
The present invention relates to platinum (II) complexes showing antitumor activity and having the formulae and wherein the stereoisomerism of 1,2-diaminocyclohexane is cis-, trans(+) or trans(-) and R<1> and R<2> when taken together represents a thymidylato-, phosphonoacetato-, or hydroxymethylphosphonato group. The invention also relates to a process for preparing these compounds and to pharmaceutical compositions containing such a complex.
Inventors:
ROBAATO JEIMUZU SUPIA
DEIUITSUDO FUIRITSUPU SUCHUWAATO
DEIUITSUDO FUIRITSUPU SUCHUWAATO
Application Number:
JP27127585A
Publication Date:
October 05, 1990
Filing Date:
December 02, 1985
Export Citation:
Assignee:
BRISTOL MYERS CO
International Classes:
A61K31/69; A61K31/28; A61K31/282; A61K31/66; A61K31/70; A61K31/7135; A61P35/00; C07C211/65; C07F9/38; C07F15/00; C07H23/00
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