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Document Type and Number:
Japanese Patent JPH03394
Kind Code:
B2
Abstract:
New heterocyclic nitriles of the formula: (I) wherein (i) Het represents a heterocyclic radical of aromatic character containing one or two nitrogen atoms selected from pyrid-3-yl, pyrid-4-yl, pyridazinyl, pyrazinyl, pyrimidinyl, quinolyl, imidazolyl, naphthyridinyl, quinoxalinyl and quinazolinyl, X represents an oxygen atom and Y represents a valency bond or a methylene radical, or altenatively X represents a sulphur atom and Y represents a sulphur atom, a valency bond or a methylene radical, or (ii) Het represents the pyrid-2-yl radical, X represents an oxygen atom and Y represents a valency bond or a methylene radical, or alternatively X represents a sulphur atom and Y represents a sulphur atom or a methylene radical, are useful, in particular, as intermediates for the preparation of therapeutically useful heterocyclic thioformamides by converting the depicted cyano radical into a grouping -CSNHR wherein R represents a hydrogen atom or an alkyl (C1-4) radical.

Inventors:
JANNKUROODO ARUUPU
JAN BUSHOODON
DANIERU FUARUJU
KUROODO JEEMUSU
Application Number:
JP13806382A
Publication Date:
January 07, 1991
Filing Date:
August 10, 1982
Export Citation:
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Assignee:
RHONE POULENC SANTE
International Classes:
A61K31/33; C07D405/04; C07D409/04; C07D411/04; C07D471/04



 
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