Title:
【発明の名称】精神分裂症用薬剤
Document Type and Number:
Japanese Patent JPH03500641
Kind Code:
A
Abstract:
This invention provides a method for treating the symptoms of schizophrenia which comprises administering to a schizophrenic an effective amount of a compound selected from the group consisting of optically-active or racemic compounds represented by the general formula: wherein R1 is selected from the group consisting of organic radicals having fused rings, phenyl, pyridyl +TR X is oxygen or sulfur, Y, if present, is selected from the group consisting of hydroxy, nitro, cyano, azido, amino, acylamino, carboxyamido, trifluoromethyl, sulfate, sulfonamido halogen, hydrocarbyl and hetero atom-substituted hydrocarbyl radicals, wherein said heteroatoms are selected from the group consisting of halogen, nitrogen, oxygen, sulfur and phosphorus and said hydrocarbyl radicals comprise from 1 to 12 carbon atoms, and a is an integer between zero and 3. R2, R3 and R4 are each selected from the group consising of H and OA, A is H or is selected from the group consisting of hydrocarbyl radicals, or R5 is selected from the group consisting of hydrocarbyl radicals and n is 2 or 3; with the proviso that at least one of R2, R3 and R4 is H, that at least one of R2, R3 and R4 is not H and that R2 and R4 are not both OA, except that when R1 is m-hydroxyphenyl, phenyl or 2-thienyl, the compound is optically-active.
Inventors:
Horn, Alan Es
Application Number:
JP50458188A
Publication Date:
February 14, 1991
Filing Date:
April 29, 1988
Export Citation:
Assignee:
Fitbee Research, Inc.
International Classes:
C07D209/08; A61K31/13; A61K31/135; A61K31/275; A61K31/34; A61K31/341; A61K31/38; A61K31/381; A61K31/40; A61K31/403; A61K31/404; A61K31/415; A61K31/44; A61K31/66; A61K31/665; A61K31/67; A61K31/675; A61P25/00; A61P25/18; C07D213/38; C07D233/64; C07D307/52; C07D333/20; C07D333/58; (IPC1-7): A61K31/13; A61K31/34; A61K31/38; A61K31/40; A61K31/44; A61K31/66; A61K31/665; A61K31/67; A61K31/675; C07D209/08; C07D213/38; C07D233/64; C07D307/52; C07D333/20
Attorney, Agent or Firm:
Kyozo Yuasa (4 outside)