Title:
【発明の名称】好中球および好酸球の共通決定部位に対して特異的な単クローン性抗体
Document Type and Number:
Japanese Patent JPH03500841
Kind Code:
A
Abstract:
A hybrid cell line capable of producing monoclonal antibodies uniquely specific to human neutrophils and eosinophils and exhibiting no specificity for lymphocytes, basophils and monocytes. Further there is noreactivity with acute leukemia cells. One of the partners in the hybridoma fusion of a mouse spleen cell developed from using human granulocytes as the immunization agent. The monoclonal antibody further is capable of being used to enumerate and isolate neutrophils in normal peripheral blood and possibly in blood of patients with acute leukemia.
Inventors:
Colt Light Kennis H
Hoff Heinz David E
Toudter Gully Pee
Hoff Heinz David E
Toudter Gully Pee
Application Number:
JP50413488A
Publication Date:
February 28, 1991
Filing Date:
April 25, 1988
Export Citation:
Assignee:
Coulter corporation
International Classes:
C07K16/28; C12N5/10; C12N15/02; C12P21/08; G01N33/577; C12R1/91; (IPC1-7): G01N33/577; C12P21/08; C12N15/06; C12N5/20
Attorney, Agent or Firm:
Akihide Sugimura (1 outside)