Title:
【発明の名称】デコリンによる細胞増殖の抑制
Document Type and Number:
Japanese Patent JPH03503846
Kind Code:
A
Abstract:
The present invention relates to the proteoglycan Decorin (also known as PG-II or PG-40). The invention provides cells transfected with and expressing a gene coding for Decorin. Spent culture media from such transfected cell cultures can be used to suppress the proliferation of either normal or abnormal cells. Purified Decorin can be used to suppress cell proliferation.
Inventors:
Luos Rathi, Erkiai.
Yamaguchi, Yu
Yamaguchi, Yu
Application Number:
JP50754389A
Publication Date:
August 29, 1991
Filing Date:
June 23, 1989
Export Citation:
Assignee:
La Jolla Cancer Research
International Classes:
A61K38/00; A61P9/10; A61P13/02; A61P13/12; C12N15/09; A61P15/00; A61P19/02; A61P29/00; A61P35/00; A61P43/00; C07K1/22; C07K14/00; C07K14/47; C07K14/50; C12N5/00; C12N5/02; C12N5/10; C12N15/12; C12P21/00; C12P21/02; C12R1/91; (IPC1-7): C07K15/14; C12N5/10; C12N15/12; C12P21/00
Other References:
PROC.NATL.ACAD.SCI.USA=1986
J.BIOL.CHEM=1982
J.BIOL.CHEM=1982
Attorney, Agent or Firm:
Hidesaku Yamamoto
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