Title:
【発明の名称】細胞性免疫の発生及び操作のための合成ペプチドの使用
Document Type and Number:
Japanese Patent JPH03504493
Kind Code:
A
Abstract:
Methods and compositions are provided for treating host prophylactically or therapeutically to stimulate the CTL of the host against the disease state. Particularly, a binding domain is provided which binds to one or more MHC Class I antigens, changing the restriction of the Class I antigen, so as to provide for an allogeneic response. By joining the binding domain or alpha helix to an epitope of an antigen of interest, the host may be stimulated to mount a CTL response in case of subsequent exposure or an existing disease state.
Inventors:
Goodenau, Robert Es.
Application Number:
JP50305689A
Publication Date:
October 03, 1991
Filing Date:
February 01, 1989
Export Citation:
Assignee:
The Regents of The University of California
International Classes:
C12P21/00; A61K38/00; A61K39/00; A61P37/00; C07K7/08; C07K14/00; C07K14/005; C07K14/11; C07K14/195; C12R1/91; (IPC1-7): C07K7/10; A61K37/02; A61K39/00; C07K7/08
Attorney, Agent or Firm:
Aoki Akira (4 outside)