- Patent JPH0372080

Document Type and Number:

Japanese Patent JPH0372080

Kind Code:

B2

Abstract:

7 alpha -acylthio-15,16-methylene-3-oxo-17 alpha -pregna-1,4-diene-21,17-carbolactones of the formula wherein the 15,16-methylene group can be in the alpha - or beta - configuration, and R is a lower alkyl residue, have altialdosterone activity. They are prepared from corresponding DELTA <4>-unsaturated compounds by chemical or microbiological 1,2-dehydrogenation.

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Inventors:

KURAUSU NIKISHU
DEIITAA BITORAA
HENRII RAURENTO
RUDORUFU UIIHIERUTO
UORUFUGANGU ROZERUTO

Application Number:

JP12244983A

Publication Date:

November 15, 1991

Filing Date:

July 07, 1983

Export Citation:

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Assignee:

SCHERING AG

International Classes:

C07J21/00; A61K31/585; C07J31/00; C07J53/00; C12P33/02

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