Document Type and Number:
Japanese Patent JPH0372238
Kind Code:
B2
Abstract:
The invention provides methods for preparing the various isomeric forms of 25-hydroxyvitamin D3-26,23-lactone utilizing cyanohydrin formation with readily prepared steroid materials followed by actinic radiation of the products and recovery of the desired 25-hydroxyvitamin D3-26,23-lactone. The invention also provides new intermediate compounds in their various isomeric forms derived during the process for preparing the said vitamin D3 lactones. 25-Hydroxyvitamin D3-26,23-lactone is recognized as having vitamin D-like activity and is believed to play an important role in the regulation of calcium and phosphate levels in the animal and human organism. The present invention provides a convenient method for preparing the various isomeric forms of this compound.
Inventors:
HEKUTAA EFU DERUUKA
HAINRITSUHI KEE SHUNOOZU
HAABAATO II PAREN
JOSEFU KEE UITSUKUMAN
MEARII EI FUIBITSUTSUANI
HAINRITSUHI KEE SHUNOOZU
HAABAATO II PAREN
JOSEFU KEE UITSUKUMAN
MEARII EI FUIBITSUTSUANI
Application Number:
JP162190A
Publication Date:
November 18, 1991
Filing Date:
January 10, 1990
Export Citation:
Assignee:
UISUKONSHIN ARAMUNI RISAACHI FUAUNDEESHON
International Classes:
C07C69/73; A61K31/575; A61K31/58; A61K31/59; A61P3/02; A61P3/14; A61P43/00; C07C59/46; C07C59/62; C07C69/732; C07C69/734; C07C401/00; C07D307/33; C07D407/12; C07F7/18; C07J1/00; C07J9/00; C07J17/00
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