Document Type and Number:
Japanese Patent JPH0438756
Kind Code:
B2
Abstract:
Novel carbapenem compounds, (1R,5S,6S)-2-substituted thio-6-[(R)-1-hydroxyethyl]-1-methyl-carbapenem-3-carboxylic acid derivatives. These carbapenem compounds are represented by the following formula having a beta-coordinated methyl group introduced into the 1-position and a 4-pyrazolizinylthio group or a 6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazolium-6-ylthio group introduced into the 2-position. In the formula, R<1> represents a radical of the formula and R<2> is a hydrogen atom or an anion charge. They have antibacterial activity, and are used for prevention and treatment of bacterial infections as antibacterial agents. A process for producing these carbapenem compounds is also provided.
Application Number:
JP3103388A
Publication Date:
June 25, 1992
Filing Date:
February 15, 1988
Export Citation:
International Classes:
C07D477/00; A61K31/397; A61K31/415; A61P31/04; C07D477/20; C07D519/00
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