Title:
【発明の名称】ペネムおよびカルバペネム製造のための中間体化合物の製造法
Document Type and Number:
Japanese Patent JPH04500077
Kind Code:
A
Abstract:
Novel and useful silylenol intermediates useful for preparing penem and carbapenem antibacterials are disclosed. Such silyenol intermediates are of the formula: wherein J is -SiR<1>R<2>R<3>; R<1>, R<2> and R<3> independently represent lower alkyl or phenyl, T is hydrogen, or a blocking group T min , wherein T min is phenyl; phenyl substituted with loweralkyl, alkoxy or halogen; phenylalkyl; -CR<5>R<6>R<7> wherein R<5> and R<6> independently represent hydrogen or loweralkyl, and R<7> represents phenyl, phenyl substituted with loweralkyl, alkoxy or halogen, phenylalkyl, alkoxy, phenoxy, phenoxy substituted with loweralkyl, alkoxy or halogen, or -CR<8>=CR<9>R<1><0> wherein R<8>, R<9> and R<1><0> independently represent hydrogen or loweralkyl; and Ar is phenyl or phenyl substituted with nitro (-NO2), lower alkyl, alkoxy, or halo.
Inventors:
Car cup, michael pee
MacConby, Stuart W
MacConby, Stuart W
Application Number:
JP50132190A
Publication Date:
January 09, 1992
Filing Date:
December 01, 1989
Export Citation:
Assignee:
SCHERING CORPORATION
International Classes:
C07D205/08; C07D303/48; C07F7/18; (IPC1-7): C07D205/08; C07F7/18
Attorney, Agent or Firm:
Kyozo Yuasa (6 people outside)