【発明の名称】ヒトインシュリン類似物質

Title:

【発明の名称】ヒトインシュリン類似物質

Document Type and Number:

Japanese Patent JPH04502465

Kind Code:

A

Abstract:

Human insulin analogues having a positively charged amino acid residue, i.e. Lys or Arg, in position B28, i.e. in position 8 in the B-chain calculated from [Gly^B20], and optionally being further modified in the C-terminal end of the B-chain from [Phe^B24] to the C-terminal amino acid residue and optionally A21 and/or B3 being different from Asn as well as insulin preparations containing the human insulin analogues are provided.

Inventors:

Barschmitt, Pell
Branje, Jens Jergen File Girl

Application Number:

JP50169890A

Publication Date:

May 07, 1992

Filing Date:

December 15, 1989

Export Citation:

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Assignee:

NOVO NORDISK AKTIE SELSXAB

International Classes:

A61K9/08; A61K9/107; A61K38/28; A61P3/08; A61P3/10; C12N15/09; C07K7/00; C07K14/575; C07K14/62; C12N15/17; C12P21/02; C12P21/06; A61K38/00; C12R1/865; (IPC1-7): A61K37/26; C07K7/40; C07K99/46; C12N15/17; C12P21/02; C12P21/06

Attorney, Agent or Firm:

Aoki Akira (3 outside)

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